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N1-Methyl-Pseudouridine-5'-Triphosphate: Transforming mRN...
2025-10-19
N1-Methyl-Pseudouridine-5'-Triphosphate empowers researchers to produce highly stable, low-immunogenicity mRNA for translation fidelity-critical applications like next-generation vaccines. Its use in in vitro transcription workflows dramatically enhances RNA stability and translational efficiency—proving essential for both mRNA vaccine development and advanced RNA-protein interaction studies.
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N1-Methylpseudouridine: Mechanistic Insight and Strategic...
2025-10-18
This thought-leadership article explores the transformative role of N1-Methylpseudouridine in mRNA therapeutics, providing a mechanistic deep dive, experimental rationale, and strategic guidance for translational researchers. By integrating evidence from recent cancer metastasis studies and highlighting best practices in mRNA modification, the article positions N1-Methylpseudouridine as an essential tool in overcoming immunogenicity and translation barriers, advancing applications in cancer, neurodegenerative, and metabolic disease models.